New Farm Brisbane: Inner-city suburb rocked by explosion as house fire badly burns two people with three others treated for smoke inhalation

At least 10 fire crews have rushed to the scene of a house fire which caused an explosion in an inner-city suburb of Brisbane.

Residents reported hearing an explosion on the corner of Bowen Terrace and Oxley Lane, New Farm around 9.15am on Saturday morning.

On arrival emergency services discovered two people badly burnt who were transported to hospital in a critical condition.

Three more people were treated for smoke inhalation. 

Residents reported hearing an explosion on the corner of Bowen Terrace and Oxley Lane, New Farm around 9.15am on Saturday morning

Residents reported hearing an explosion on the corner of Bowen Terrace and Oxley Lane, New Farm around 9.15am on Saturday morning

On arrival emergency services discovered two people badly burnt who were transported to hospital in a critical condition

On arrival emergency services discovered two people badly burnt who were transported to hospital in a critical condition 

On Facebook Queensland Ambulance Service said the blaze, initially described as 'out of control', had now been contained

On Facebook Queensland Ambulance Service said the blaze, initially described as 'out of control', had now been contained

On Facebook Queensland Ambulance Service said the blaze, initially described as 'out of control', had now been contained.

A Queensland Ambulance spokesperson said the critically injured pair had been transported to the Royal Brisbane and Women's Hospital where they were placed in induced comas. 

'We assessed five patients at the scene, two were in critical condition and both of those suffered extensive burns,' she said. 

'They were transported transported to the Royal Brisbane and Women's Hospital.

'A third patient there are suffered some smoke inhalation and was transported in a stable condition through to the Royal Brisbane and Women's Hospital.

'The remaining two patients both did suffer some smoke inhalation, however they declined any hospitalizations so they were left at the scene.'

Queensland Police Inspector Karl Hahne earlier told the Courier Mail neighbours doused two occupants with water before they were treated by paramedics. 

'About 9:16am multiple calls for service were received by police, fire and ambulance. On arrival, there was a severe fire in one the units,' she said.

'(The seriously injured male and female) were incubated, placed in an induced coma, and taken to hospital.'

Motorists are advised to drive with caution and to conditions. Residents are advised to close windows and doors and, if needed, keep respiratory medications nearby. 

Police have established a crime scene.

More to come